FOSSENCE® is short chain fructo-oligosaccharide (scFOS), a soluble prebiotic dietary fibre. According to a recent scientific review article (systematic review and meta-analysis: Dou et al. 2022 ), which included 9 studies with FOS intervention wherein the duration ranged from 7 to 56 days. This meta-analysis objectively investigated the effect of FOS on bacterial communities and gastrointestinal symptoms, and reached a conclusion that FOS intervention could increase the number of Bifidobacterium spp. in the colon with profound effects on dose range i.e. 7.5–15 g/d and longer duration (>4 weeks). The dosages were also well tolerated.
